Cryo-EM structure of human TRiC-NPP state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7x0a
Q-score: 0.256
Liu C, Jin M, Wang S, Han W, Zhao Q, Wang Y, Xu C, Diao L, Yin Y, Peng C, Bao L, Wang Y, Cong Y
Commun Biol (2023) 6 pp. 531-531 [ DOI: doi:10.1038/s42003-023-04915-x Pubmed: 37193829 ]
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Htric-npp (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7x0s
Q-score: 0.469
Liu C, Jin M, Wang S, Han W, Zhao Q, Wang Y, Xu C, Diao L, Yin Y, Peng C, Bao L, Wang Y, Cong Y
Commun Biol (2023) 6 pp. 531-531 [ DOI: doi:10.1038/s42003-023-04915-x Pubmed: 37193829 ]
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- Human tric-tubulin-s3 (Complex from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
cryo-EM structure of human TRiC-ADP-AlFx
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7x0v
Q-score: 0.439
Liu C, Jin M, Wang S, Han W, Zhao Q, Wang Y, Xu C, Diao L, Yin Y, Peng C, Bao L, Wang Y, Cong Y
Commun Biol (2023) 6 pp. 531-531 [ DOI: doi:10.1038/s42003-023-04915-x Pubmed: 37193829 ]
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- Human tric-adp-alfx (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
yeast TRiC-plp2-substrate complex at S1 TRiC-NPP state
Resolution: 4.55 Å
EM Method: Single-particle
Fitted PDBs: 7ylu
Q-score: 0.104
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y
Sci Adv (2023) 9 pp. eade1207-eade1207 [ Pubmed: 36921056 DOI: doi:10.1126/sciadv.ade1207 ]
- T-complex protein 1 subunit gamma (58 kDa, Protein from Saccharomyces cerevisiae)
- Tric (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit eta (59 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit beta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit theta (61 kDa, Protein from Saccharomyces cerevisiae)
- Phosducin-like protein 2 (32 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit zeta (59 kDa, Protein from Saccharomyces cerevisiae)
- Plp2 (Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Saccharomyces cerevisiae)
- Yeast tric-plp2-substrate complex at c1 tric-npp state (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit epsilon (61 kDa, Protein from Saccharomyces cerevisiae)
yeast TRiC-plp2-substrate complex at S2 ATP binding state
Resolution: 3.91 Å
EM Method: Single-particle
Fitted PDBs: 7ylv
Q-score: 0.124
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y
Sci Adv (2023) 9 pp. eade1207-eade1207 [ Pubmed: 36921056 DOI: doi:10.1126/sciadv.ade1207 ]
- T-complex protein 1 subunit gamma (58 kDa, Protein from Saccharomyces cerevisiae)
- Tric (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit eta (59 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit beta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit theta (61 kDa, Protein from Saccharomyces cerevisiae)
- Phosducin-like protein 2 (32 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit zeta (59 kDa, Protein from Saccharomyces cerevisiae)
- Plp2 (Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit epsilon (61 kDa, Protein from Saccharomyces cerevisiae)
- Yeast tric-plp2-substrate complex at c2 atp binding state (Complex from Saccharomyces cerevisiae)
yeast TRiC-plp2-tubulin complex at S3 closed TRiC state
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 7ylw
Q-score: 0.318
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y
Sci Adv (2023) 9 pp. eade1207-eade1207 [ Pubmed: 36921056 DOI: doi:10.1126/sciadv.ade1207 ]
- Tubulin beta chain (50 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit eta (59 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit beta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit theta (61 kDa, Protein from Saccharomyces cerevisiae)
- Phosducin-like protein 2 (32 kDa, Protein from Saccharomyces cerevisiae)
- Tric, tubulin beta chain (Complex from Saccharomyces cerevisiae)
- Plp2 (Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit zeta (59 kDa, Protein from Saccharomyces cerevisiae)
- Aluminum fluoride (83 Da, Ligand)
- Water (18 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit gamma (65 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit epsilon (61 kDa, Protein from Saccharomyces cerevisiae)
- Yeast tric-plp2-tubulin complex at c3 closed tric state (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
yeast TRiC-plp2-actin complex at S4 closed TRiC state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ylx
Q-score: 0.353
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y
Sci Adv (2023) 9 pp. eade1207-eade1207 [ Pubmed: 36921056 DOI: doi:10.1126/sciadv.ade1207 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tric (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit eta (59 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit beta (57 kDa, Protein from Saccharomyces cerevisiae)
- Yeast tric-plp2-actin complex at c4 closed tric state (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit theta (61 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit zeta (59 kDa, Protein from Saccharomyces cerevisiae)
- Plp2 (Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Saccharomyces cerevisiae)
- Phosducin-like protein 2 (32 kDa, Protein from Saccharomyces cerevisiae)
- Aluminum fluoride (83 Da, Ligand)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit gamma (65 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit epsilon (61 kDa, Protein from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
yeast TRiC-plp2 complex at S5 closed TRiC state
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7yly
Q-score: 0.354
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y
Sci Adv (2023) 9 pp. eade1207-eade1207 [ Pubmed: 36921056 DOI: doi:10.1126/sciadv.ade1207 ]
- T-complex protein 1 subunit epsilon (61 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tric (Complex from Saccharomyces cerevisiae)
- T-complex protein 1 subunit eta (59 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit beta (57 kDa, Protein from Saccharomyces cerevisiae)
- Phosducin-like protein 2 (32 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit theta (61 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit zeta (59 kDa, Protein from Saccharomyces cerevisiae)
- Plp2 (Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Saccharomyces cerevisiae)
- Aluminum fluoride (83 Da, Ligand)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Saccharomyces cerevisiae)
- T-complex protein 1 subunit gamma (65 kDa, Protein from Saccharomyces cerevisiae)
- Tric-plp2 complex at c5 closed tric state (Complex from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of human TRiC-tubulin-S1 state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7wz3
Q-score: 0.227
Liu C, Jin M, Wang S, Han W, Zhao Q, Wang Y, Xu C, Diao L, Yin Y, Peng C, Bao L, Wang Y, Cong Y
Commun Biol (2023) 6 pp. 531-531 [ DOI: doi:10.1038/s42003-023-04915-x Pubmed: 37193829 ]
- Tric-tubulin-s1 (Complex from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)